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Biogenics Research Institute
Other Respiratory Tract Disorders
Hypersensitivity Pneumonitis
Biogenics, Inc
Idiopathic Intersitial Lung Disease

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Professional Curriculum Vitae

A. IDENTIFICATION

       
  1. Name: Robert L. Jacobs, M.D.
    2.    
  2. Birthdate: 9 November 1936
    3.    
  3. Private Practice Address
    8285 Fredericksburg Rd.
    San Antonio TX 78229
    4.    
  4. Research Address
    Biogenics Research Institute
    8233 Fredericksburg Rd.
    San Antonio TX 78229
    Biogenics Research Institute
    8229 Fredericksburg Rd.
    San Antonio TX 78229

B. BACKGROUND

       
  1. Undergraduate Education
    a. School: University of Alabama
    b. Major: Biology
    c. Degree: Bachelor of Science
    d. Date: 1964
    2.    
  2. Professional Education
    a. School: Medical College of Alabama
    b. Degree: M.D.
    c. Date: 1968
    3.    
  3. Postgraduate Education
    a. Internship - July 1968 - June 1969, Malcolm Grow USAF Medical Center - Washington, D.C.
    b. Residency - July 1969 - June 1971, Wilford Hall USAF Medical Center - San Antonio, TX
    c. Fellowship - July 1971 - June 1973, Wilford Hall USAF Medical Center - San Antonio, TX

C. LICENSURES AND CERTIFICATION

       
  1. Professional Licensure
    a. Alabama, #6216, 20Apr73.
    b. Texas, #E1627, 4Dec73
    2.    
  2. Specialty Board Certification
    a. Medicine, # 100176, 15 Jul 69
    b. Internal Medicine, 39117, 19 Jun 74
    c. Allergy & Immunology, 1204, 21 Oct 75
    3.    
  3. Recertification
    a. Allergy & Immunology
    b. Certificate # 291
    c. Date 3 Oct 83

D. PROFESSIONAL ORGANIZATION MEMBERSHIP

       
  1. Society of Principal Investigators
    2.    
  2. Society of Medical Consultants to the Armed Forces
    3.    
  3. American Academy of Allergy, Asthma and Immunology
    4.    
  4. American College of Allergy, Asthma and Immunology
    5.    
  5. San Antonio Allergy, Asthma, and Immunology Society
    6.    
  6. Bexar County Medical Society
    7.    
  7. Texas Allergy Society
    8.    
  8. Texas Medical Association
E. HONORS AND EXECUTIVE POSITIONS HELD
       
  1. Staff Allergist
    Department of Allergy and Immunology
    Wilford Hall USAF Medical Center, 1973 - 1974
    2.    
  2. Chairman
    Department of Allergy and Immunology
    Wilford Hall USAF Medical Center, 1974 - 1984
    3.    
  3. Training Program Director
    Department of Allergy and Immunology
    Wilford Hall USAF Medical Center, 1974 - 1984
    4.    
  4. Associate Professor of Medicine
    Uniformed Services University of the Health Sciences, 1980 - 1984
    5.    
  5. Clinical Assistant Professor of Medicine
    UT Health Science Center at San Antonio, 1980 - 1992
    6.    
  6. Clinical Associate Professor of Medicine
    UT Health Science Center at San Antonio, 1993 - 2000
    7.    
  7. Consultant to the Surgeon General in Internal Medicine Allergy and Immunology, 1977 - 1984
    8.    
  8. Special Assistant to the Surgeon General
    1979 - 1984
    9.    
  9. Colonel (Ret)
    USAF MC, 1984
    10.    
  10. Chairman Scientific Program, Southwest Allergy Forum, 1985
    11.    
  11. Associate Scientist, Department of Virology and Immunology,
    Southwest Foundation for Biomedical Research, 1985 - 1994
    12.    
  12. Reviewer
    Annals of Internal Medicine, 1980 - present
    Annals of Allergy, Asthma, and Immunology, 2001-Present
    American Journal of Respiratory and Critical Care Medicine. 2005-present
    13.    
  13. President and CEO
    Immunobionomics Laboratories, Inc. 1989 - 2007
    14.    
  14. Medical Director/Principal Investigator
    Biogenics Research Institute, 1993 - present
    15.    
  15. Sub Investigator
    Biogenics Research Institute, 2001 – present  
     
  16. Awards
    2009 Lifetime Achievement Award by San Antonio Business Journal
       

F. PUBLICATIONS

       
  1. Stern MP, Jacobs RL, Duncan GW: Complete heart block complicating hyperthyroidism. JAMA 1970;212:2117-20
    2.    
  2. Michels MI, Jacobs RL: Hypersensitivity to tetanus toxoid. J Allergy Clin Immunol 1974;53:118-9
    3.    
  3. James FK, Pence HL, Driggers DJ, Jacobs RL, Horton DE: Imported fire ant sensitivity. Studies of human reactions to fire ant venom. J Allergy Clin Immunol 1976;58:110-20
    4.    
  4. Dorman SG, Ruark GW, Agus ZS, Jacobs RL, Young R: Transient diabetes insipidus with elevated serum osmolarity associated with a benign febrile illness. Arch Int Med 1977;137:1479-81
    5.    
  5. Jacobs RL, Freedman PM, Boswell RN: Non-allergic rhinitis with eosinophilia (NARES) syndrome. Clinical and immunological characterization. J Allergy Clin Immunol 1981;67:253-62
    6.    
  6. Jacobs RL: A practical classification of chronic rhinitis. J Respir Dis 1981;2 (5):20
    7.    
  7. Jacobs RL, Rake GW, Fournier DC, Chilton RJ, Culver WG, Beckmann CH: Potentiated anaphylaxis in patients with drug-induced beta-adrenergic blockade. J Allergy Clin Immunol 1981,68:125-27 
       
  8. Jacobs RL, Lowe RS, Lanier BQ: Adverse reactions to tetanus toxoid. JAMA 1982;247:40-2
    9.    
  9. Jacobs RL, Lowe RS, Lanier BQ: Unerwunschte reaktionen auf tetanustoxoid. JAMA - D 1982;1 (7):383-6
    10.    
  10. Jacobs RL, Koppes GW: Myocardial necrosis associated with isoproterenol abuse: A ten year follow-up. Tex Med 1982;78:58-60
    11.    
  11. Jacobs RL, Rake GW, Fournier DC, Chilton RJ, Culver WG, Beckmann CH: Glucagon in anaphylaxis - reply. J Allergy Clin Immunol 1982;69:331-32
    12.    
  12. Nelson BL, Jacobs RL: Response of the non-allergic rhinitis with eosinophilia (NARES) syndrome to 4% cromolyn sodium nasal solution. J Allergy Clin Immunol 1982;70:125-28
    13.    
  13. Strom GB, Boswell RN, Jacobs RL: In vivo and in vitro comparison of fire ant venom and fire ant whole body extract. J Allergy Clin Immunol 1983;72:46-53
    14.    
  14. Rake GW, Jacobs RL: Anaphylactoid reactions to tolmetin and zomepirac. Ann Allergy 1983;50:323-25
    15.    
  15. Jacobs RL, Freda AJ, Culver WG: Primary nasal polyposis. Ann Allergy 1983;51:500-05
    16.    
  16. Jacobs RL: Reactions to tetanus toxoid. JAMA 1983;250:1273-74
    17.    
  17. Hallett JS, Jacobs RL: Recurrent bronchitis: Therapy as usual? J Respir Dis 1984;5:80
    18.    
  18. Jacobs RL, Lux GK, Spielvogel TL, Eichberg JW, Gleiser CA: Nasal polyposis in a chimpanzee. J Allergy Clin Immunol 1984;74:61-3
    19.    
  19. Sacha RF, Tremblay NF, Jacobs RL: Chronic cough, sinusitis, and hyperactive airways in children: An often overlooked association. Ann Allergy 1985;54:195-98
    20.    
  20. Hallett JS, Jacobs RL: Recurrent acute bronchitis: The association with undiagnosed bronchial asthma. Ann Allergy 1985;55:568-70
    21.    
  21. Anderson DC, Schmalsteig FC, Finegold MJ, Hughes BJ, Rothlein R, Miller LJ, Kohl S, Tosi MF, Jacobs RL, Waldrop TC, Goldman AS, Shearer WT, Springer TA: The severe and moderate phenotypes of heritable Mac-1, LFA-1 deficiency: Their quantitative definition and relation to leukocyte dysfunction and clinical features. J Inf Dis 1985;152:668-89
    22.    
  22. Jacobs RL, Patterson R: Immunotherapy v Pharmacotherapy for allergy sufferers. Respir Med Today 1986;2 (3):4-14
    23.    
  23. Jacobs RL, Thorner RE, Holcolm JR, Schwietz LA, Jacobs FO: Hypersensitivity pneumonitis caused by Cladosporium in an enclosed hot-tub area. Ann Int Med 1986;105:204-06
    24.    
  24. Halsey AB, Martin ME, Ruff ME, Jacobs FO, Jacobs RL: Sunflower oil is not allergenic to sunflower seed-sensitive patients. J Allergy Clin Immunol 1986;78:408-10.
    25.    
  25. Waldrop TC, Anderson DC, Schmalstieg FC, Hallmon WW, Jacobs RL: Peridontol manifestations of the heritable Mac-1, LFA-1 deficiency syndrome-Clinical, histopathologic, and molecular characteristics. J Peridontol 1987;58:400-16
    26.     
  26. Jacobs RL: Non-allergic chronic rhinitis syndromes. Immunol Allergy Clin North Amer 1987;7:93-103 
        
  27. Jacobs RL, O'Gorman LA, Jacobs, FO: Environmentally-induced "asthma". J Allergy Clin Immunol 1987;79:140 (Abst. #61)
    28.     
  28. Jacobs RL, Andrews CP, Jacobs FO: Hypersensitivity pneumonitis treated with an electrostatic dust filter. Ann Int Med 1989;110:115-18
    29.     
  29. Jacobs RL, Meltzer EO, Selner JC, Slavin RG: Rhinitis: Not just hay fever. Patient Care 1989;23 (6);168-84
    30.     
  30. Jacobs RL, Hoberman LJ, Goldstein HM: Angioedema of the small bowel caused by an angiotensin-converting enzyme inhibitor. Amer Jour Gastroen
    1994;89:127-28
    31.     
  31. Jacobs RL, Hoberman LJ, Goldstein HM: Angioedema of the small bowel caused by an angiotensin-converting enzyme inhibitor. Amer Jour Gastroen 1994;89:1118 (letter)
    32.      
  32. Jacobs RL, Andrews CP, Coalson J: Organic antigen-induced interstitial lung disease: Diagnosis and management. Ann Allergy Asthma Immunol 2002:88:30-41.
    33.     
  33. Jacobs RL: Hypersensitivity Pneumonia: UIP/IPF histopathological presentation. J Allergy Clin Immunol 2002;110:532-533.
    34.     
  34. Ratner PH, Howland WC, Jacobs RL, et al: Relief of Sinus Pain and Pressure with Fluticasone Propionate Aqueous Nasal Spray: A Placebo-Controlled Trial in Patients with Allergic Rhinitis. Allergy and Asthma Proc. 2002;23:259-263.
    35.     
  35. Gross G, Jacobs RL, Woodworth TH, et al: Comparative efficacy, safety, and effect on quality of life of triamcinolone acetonide and fluticasone propionate aqueous nasal sprays in patients with fall seasonal allergic rhinitis. Ann Allergy Asthma Immunol 2002;89:56- 62.
    36.     
  36. McClusky OE, Bonham R, Fawcett W, Holcomb J, Jacobs R, Lanier B, Yates R: Black mold and human illness. Texas Med. 2002; 98:53-56.
    37.     
  37. Jacobs RL, Andrews CP: Hypersensitivity pneumonia - NSIP histopathological presentation: A study in diagnosis and long-term management. Ann Allergy Asthma Immunol. 2003; 90: 265-270.
    38.     
  38. Bardana EJ, Chapman JA, Charlesworth EN, Jacobs RL, Terr AI: Crossing over to the dark side of the mold issue: A dissenting view. Ann Allergy Asthma Immunol. 2003;91: 212-213 (letter).
    39.     
  39. Chapman JA, Terr AI, Jacobs RL, Charlesworth EN, Bardana EJ: Toxic mold: phantom risk vs. science. Ann Allergy Asthma Immunol. 2003; 91: 222-232.

  40. Pauweis RA, Pedersen S, Busse WW, et al:  Early intervention with budesonide in mild persistent asthma:  a randomized, double-blind trial.  Lancet. 2003 Mar 29; 361 (9363):  1071-6.

  41. Jacobs RL, Andrews CP, Coalson JJ: Hypersensitivity Pneumonitis: Beyond classic occupational disease-changing concepts of diagnosis and management. Ann Allergy Asthma Immunol. 2005;95: 115-128.

  42. O'Byrne PM, Pedersen S, Busse WW, et al:  Effects of early intervention with inhaled budesonide on lung function in newly diagnosed asthma.  Chest.  2006 Jun; 129(6):  1478-85
    43.     
  43. Busse WW, Pedersen S, Pauwels RA, et al. The inhaled steroid treatment as regular therapy in early asthma (START) study 5 year follow-up; effectiveness of early intervention with budesonide in mild persistent asthma. J Allergy Clin Immunol. 2008;121:1167-74.
    44.     
  44. Jacobs RL. Hypersensitivity pneumonitis may be home-induced by common domestic mold spores. J Allergy Clin Immunol. 2008;122:428.
    45.     
  45. Jacobs RL, Lieberman P, Kent E, et al. Weather/temperature-sensitive vasomotor rhinitis may be refractory to intranasal corticosteroid treatment. Allergy Asthma Proc. 2009; 30 120-127.
    46.     
  46. Andrews CP, Martin BG, Jacobs RL, et al: Fluticasone furoate nasal spray is more effective than fexofenadine for nighttime symptoms of seasonal allergy. Allergy Asthma Proc 2009; 30:128-138.

  47. Jacobs RL, Martin B, Hampel F, et al. Effectiveness of fluticasone furoate 110 micrograms once daily in the treatment of nasal and ocular symptoms of seasonal allergic rhinitis in adults and adolescents sensitized to mountain cedar pollen. Current Medical Research and Opinion. 2009;25:1393-140 

G. Presentations:

       
  1. Hypersensitivity Pneumonitis: The View from the Front. Presented to the Colorado Allergy Society. October, 2005
    2.    
  2. Hypersensitivity Pneumonitis: Are Diagnostic Criteria Too Restrictive? Presented at Allergy/Immunology Grand Rounds, National Jewish and Univ of Colorado. October, 2005
    3.    
  3. Home Related Hypersensitivity Pneumonitis. Presented at the 4th International WASOG Conference on Diffuse Lung Disease. Tokyo, Japan. October, 2007.